THE "BEST" ANTIBIOTIC SENSITIVITY CHART EVER

THE "BEST" ANTIBIOTIC SENSITIVITY CHART EVER (at least the best we could make)

Created by James McCormack, BSc(Pharm), PharmD and Fawziah Lalji, BSc(Pharm), PharmD, FCSHP with assistance from Tim Lau

Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC

Bacteria

Gram Positive Cocci

Gram Negative Bacilli

Gram Negative Coccobacilli

Anaerobes

Atypicals

Streptococci

Staphylococci

Non-beta-lactamase producing Escherichia coli,

Klebsiella pneumoniae, Haemophilus influenzae

Beta-lactamase producing Escherichia coli,

Klebsiella pneumoniae, Haemophilus influenzae

SPACE

Serratia marcescens, Proteus mirabilis, Acinetobacter sp., Citrobacter sp., Enterobacter sp.

ESBL

(Extended spectrum beta-lactamase producing) Escherichia coli, Klebsiella pneumoniae

CRE

(Carapenem-resistant Enterobacteriaceae)

Pseudomonas aeruginosa

Neisseria meningitidis

Neisseria gonorrhea

Above the diaphragm (Peptostreptococcus)

Below the diaphragm (Bacteroides sp)

Clostridium difficile

Mycoplasma pneumoniae, Chlamydophila spp

Legionella pneumophila

Chlamydia trachomatis

Streptococci (pneumoniae/ pyogenes/ viridans group)

Enterococci (Group D strep)

Staph epidermidis (coagulase negative)

Staph aureus

(Methicillin sensitive)

Community acquired (Methicillin resistant)

Hospital acquired (Methicillin resistant)

Location

Brain, oral, respiratory tract, heart, skin

Intraabdominal, urinary tract

Skin, prosthetics

Oral, respiratory tract, heart, skin, bones/joint

Brain, respiratory tract, intraabdominal, urinary tract

Brain

Pelvic inflammatory disease/STI

Oral, respiratory tract

Intraabdominal, pelvic inflammatory disease

Intraabdominal

Respiratory tract

Pelvic inflammatory disease/STI

Penicillins

Pencillin V/G

Pencillin G-IV

Pencillin V/G

Amoxicillin/ampicillin

Ampicillin-IV

Amoxicillin/ampicillin

Cloxacillin

Amoxicillin-clavulanate

Piperacillin-tazobactam

Cephalosporins

Cefazolin/cephalexin

Cefuroxime

Cefoxitin

Ceftriaxone/cefotaxime

Cefixime

Ceftazidime

Ceftolozane - tazobactam

Ceftolozane-tazobactam

Cefipime

Ceftibiprole

Carbapenems

Meropenem/imipenem/doripenem

Ertapenem

Macrolides

Erythromycin

Clarithromycin/azithromycin

Clarithromycin/azithromycin JUST H.flu

JUST Azithromycin

Clarithromycin/azithromycin

JUST Azithromycin

Tetracyclines

Tetracycline/doxycycline

Tetracycline/doxycycline JUST H.flu

Tetracycline/doxycycline

Tigecycline

Fluoroquinolones

Ciprofloxacin/norfloxacin BUT JUST bladder infections for norfloxacin

JUST Ciprofloxacin

Levofloxacin/moxifloxacin

JUST Moxifloxacin

Levofloxacin/moxifloxacin

Aminoglycosides

Gentamicin/tobramycin/amikacin

Polymyxin

Colistin/polymyxin B

Lincosamides

Clindamycin

Glycopeptides/lipoglycopeptides

Vancomycin/daptomycin

Vancomycin oral

Oxazolidinones

Linezolid/tedizolid

Trimethoprim-Sulfamethoxazole

Trimethoprim-sulfamethoxazole

Chloramphenicol

Metronidazole

Nitrofurantoin/fosfomycin

(JUST BLADDER INFECTIONS)

Nitrofurantoin/fosfomycin JUST E.faecalis

Nitrofurantoin/fosfomycin

Rifampin

Fidaxomicin

Cloxacillin and clindamycin typically have less than 40% activity for S.epidermidis, thus usage depends on local susceptibility data

Enterococci has two main species - Enterococcus faecalis and Enterococcus faecium; the antibiotics listed are active against E.faecalis, but have limited activity for E.faecium Cephalosporins have in-vitro activity for SPACE organisms but induce production of beta-lactamases

Tigecycline has no activity against Pseudomonas aeruginosa, but for Acinetobacter it depends on local susceptibility data; Tigecycline is active against SPACE organisms, but for Proteus spp it depends on local susceptibility data

NOVEMBER 2019